| CAS No. | 50405-58-8 |
|---|---|
| MDL No. | N/A |
| MF | C13H13NO2 |
| MW | 215.25 |
| InChI Key | AVLZAVSZOAQKRC-UHFFFAOYSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
SYC-435 is a cyclic hydroxamic acid, specifically 1-hydroxypyridin-2(1H)-one, with methyl and benzyl groups at positions 4 and 6, respectively. It is a potent inhibitor of mutant isocitrate dehydrogenase 1, with Ki values of 190 nM for the R132H mutant and 120 nM for the R132C mutant. It functions as an EC 1.1.1.42 inhibitor and an antineoplastic agent. It belongs to benzenes, pyridones, and cyclic hydroxamic acids.
| CAS No. | 50405-58-8 |
|---|---|
| Product Name | TC-E 5008 |
| Heavy Atom Count | 16 | Rotatable Bond Count | 2 |
| Atom Stereo Count | 0 | Bond Stereo Count | 0 |
| HBA | 3 | HBD | 1 |
| TPSA | 42.230 Ų | Charge | 0 |
| Exact Mass | 215.09463 | Complexity | 543.60 |
| pKa | 11.433 | XLogP | 1.985 |