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Chemical structure of CAS 504-24-5

4-Aminopyridine

CAS No.504-24-5
MDL No.MFCD00006439
MFC5H6N2
MW94.11
InChI KeyNUKYPUAOHBNCPY-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
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Product Information

4-Aminopyridine is an aromatic amine and aminopyridine with an amino group at position 4 of the pyridine ring. It functions as a potassium channel blocker, avicide, and orphan drug in the US, used to improve walking in adults with multiple sclerosis.

CAS No.504-24-5
Product Name4-Aminopyridine

Biological Targets

KCNQ1·KCND3·KCNH2·KCNA2·KCNA1·

Associated Conditions

cerebral palsy·carpal tunnel syndrome·Renal insufficiency·Ischemic stroke·obstructive sleep apnea·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Dendritic coincidence detection of EPSPs and action potentials.

Nature neuroscience • Vol. 4, Issue 1 • 2001
PMID: 11135646DOI: 10.1038/82910

Role of potassium channels in regulation of brain arteriolar tone: comparison of cerebrum versus brain stem.

Stroke • Vol. 32, Issue 1 • 2001
PMID: 11136940DOI: 10.1161/01.str.32.1.218

Cold transduction by inhibition of a background potassium conductance in rat primary sensory neurones.

Neuroscience letters • Vol. 297, Issue 3 • 2001
PMID: 11137755DOI: 10.1016/s0304-3940(00)01694-3

Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens.

The Journal of neuroscience : the official journal of the Society for Neuroscience • Vol. 21, Issue 1 • 2001
PMID: 11150326PMC: PMC6762427DOI: 10.1523/JNEUROSCI.21-01-00109.2001

Documentation

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