Product Information

CAS No.	49863-47-0
Product Name	G-418

Heavy Atom Count	34	Rotatable Bond Count	6
Atom Stereo Count	15	Bond Stereo Count	0
HBA	14	HBD	10
TPSA	248.390 Å²	Charge	0
Exact Mass	496.27444	Complexity	675.27
pKa	7.130	XLogP	-5.613

Studies related to this compound and its mechanism of action

Translational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivo.

Human molecular genetics • Vol. 18, Issue 7 • 2009

PMID: 19150990 PMC: PMC2655772 DOI: 10.1093/hmg/ddp030

G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis.

American journal of physiology. Renal physiology • Vol. 295, Issue 3 • 2008

PMID: 18614622 PMC: PMC2653109 DOI: 10.1152/ajprenal.00015.2008

Restoration of W1282X CFTR activity by enhanced expression.

American journal of respiratory cell and molecular biology • Vol. 37, Issue 3 • 2007

PMID: 17541014 PMC: PMC1994229 DOI: 10.1165/rcmb.2006-0176OC

Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation.

The Journal of biological chemistry • Vol. 281, Issue 6 • 2006

PMID: 16354666 PMC: PMC1472404 DOI: 10.1074/jbc.M511295200

G-418

CAS No.	49863-47-0
MDL No.	N/A
MF	C₂₀H₄₀N₄O₁₀
MW	496.60
InChI Key	BRZYSWJRSDMWLG-DJWUNRQOSA-N

CUSTOM SYNTHESIS PRECLINICAL SUPPORT

Pricing & Availability

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.	49863-47-0
Product Name	G-418

Heavy Atom Count	34	Rotatable Bond Count	6
Atom Stereo Count	15	Bond Stereo Count	0
HBA	14	HBD	10
TPSA	248.390 Å²	Charge	0
Exact Mass	496.27444	Complexity	675.27
pKa	7.130	XLogP	-5.613

G-418

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Product Information

Properties

G-418

Pricing & Availability

Product Information

Properties

Documentation

G-418

Pricing & Availability

Product Information

Properties

Related Articles

Translational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivo.

G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis.

Restoration of W1282X CFTR activity by enhanced expression.

Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation.

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G-418

Pricing & Availability

Product Information

Properties

Related Articles

Translational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivo.

G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis.

Restoration of W1282X CFTR activity by enhanced expression.

Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation.

Similar Products

Gentamicin C1A

Micronomicin

Documentation