| CAS No. | 497839-62-0 |
|---|---|
| MDL No. | MFCD19708018 |
| MF | C27H32N6 |
| MW | 440.60 |
| InChI Key | OONFNUWBHFSNBT-HXUWFJFHSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
AEE788 is a 6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine with R-configuration. It is a potent inhibitor of human EGFR, VEGFR, and HER2 receptor tyrosine kinases, exhibiting anticancer and antiangiogenic activity. It functions as an epidermal growth factor receptor antagonist, EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, antineoplastic agent, angiogenesis inhibitor, trypanocidal drug, and apoptosis inducer.
| CAS No. | 497839-62-0 |
|---|---|
| Product Name | 6-(4-((4-Ethyl-1-piperazinyl)methyl)phenyl)-N-((1R)-1-phenylethyl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine |