CAS 475110-96-4 – 2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl…

CAS No.

475110-96-4

MDL No.

MFCD08705334

C₁₉H₂₁F₂N₇O₂

417.40

InChI Key

HGVNLRPZOWWDKD-UHFFFAOYSA-N

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Pack Size

Purity

Price

Availability

Action

On Request

Custom synthesis and bulk supply options are available upon request.

Product Information

ZSTK-474 is a triamino-1,3,5-triazine in which two hydrogens are replaced by morpholin-4-yl groups and one hydrogen is replaced by a 2-(difluoromethyl)benzimidazol-1-yl group. It is a phosphatidylinositol 3-kinase inhibitor, acting as an EC 2.7.1.137 inhibitor and an antineoplastic agent. It belongs to morpholines, benzimidazoles, triamino-1,3,5-triazines, and organofluorine compounds.

CAS No.	475110-96-4
Product Name	2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-1H-benzimidazole

Biological Targets

PIK3R1·PIK3CB·PIK3CG·PIK3CA·PIK3R2·

Associated Conditions

neoplasm

* The information provided here is compiled from public sources and is for reference only.

2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-1H-benzimidazole

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Documentation

2-(Difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-1H-benzimidazole

Pricing & Availability

Product Information

Biological Profile

Properties

Biological Targets

Associated Conditions

Related Articles

The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas.

Synthesis and biological evaluation of novel analogues of the pan class I phosphatidylinositol 3-kinase (PI3K) inhibitor 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474).

Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo.

Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR39.

Documentation

Similar Products

2-(Difluoromethyl)-7-methoxy-3-[4-morpholin-4-yl-6-(1,4-oxazepan-4-yl)-1,3,5-triazin-2-yl]benzimidazol-5-amine

Zandelisib

4-(4,6-Dimorpholino-1,3,5-triazin-2-yl)aniline