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Chemical structure of CAS 474645-27-7

Monomethyl Auristatin E

CAS No.474645-27-7
MDL No.MFCD22124498
MFC39H67N5O7
MW718.00
InChI KeyDASWEROEPLKSEI-UIJRFTGLSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.474645-27-7
Product NameMonomethyl Auristatin E
Acute ToxicAcute Toxic
IrritantIrritant
Health HazardHealth Hazard
Signal Word:Danger
HCode:H300-H302-H315-H319-H330-H335-H340-H341-H360-H370-H372-H412
PCode:P203-P260-P261-P264-P264+P265-P270-P271-P273-P280-P284-P301+P316-P301+P317-P302+P352-P304+P340-P305+P351+P338-P308+P316-P316-P318-P319-P320-P321-P330-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Related Articles

Studies related to this compound and its mechanism of action

Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy.

Toxicology and applied pharmacology • Vol. 421 • 2021
PMID: 33852878DOI: 10.1016/j.taap.2021.115534

Documentation

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