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Chemical structure of CAS 471905-41-6

Mk-0752

In Stock•Starting at $333 for 25 mg•Purity ≥ 95%
CAS No.471905-41-6
MDL No.MFCD21608529
MFC21H21ClF2O4S
MW442.90
InChI KeyXCGJIFAKUZNNOR-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
25 mg98%$333In Stock
100 mg98%$793In Stock
1 g98%$4048In Stock
5 g95%+$7326In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.471905-41-6
Product NameMk-0752
CorrosiveCorrosive
IrritantIrritant
Health HazardHealth Hazard
Signal Word:Danger
HCode:H302-H318-H360-H371-H373
PCode:P203-P260-P264-P264+P265-P270-P280-P301+P317-P305+P354+P338-P308+P316-P317-P318-P319-P330-P405-P501

Related Articles

Studies related to this compound and its mechanism of action

Secretase inhibitors for the treatment of Alzheimer's disease: Long road ahead.

European journal of medicinal chemistry • Vol. 148 • 2018
PMID: 29477076DOI: 10.1016/j.ejmech.2018.02.035

Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • Vol. 29, Issue 26 • 2011
PMID: 21825264PMC: PMC3179253DOI: 10.1200/JCO.2011.35.7806

Determination of the gamma-secretase inhibitor MK-0752 in human plasma by online extraction and electrospray tandem mass spectrometry (HTLC-ESI-MS/MS).

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences • Vol. 878, Issue 25 • 2010
PMID: 20702149PMC: PMC2926936DOI: 10.1016/j.jchromb.2010.07.019

Acute gamma-secretase inhibition of nonhuman primate CNS shifts amyloid precursor protein (APP) metabolism from amyloid-beta production to alternative APP fragments without amyloid-beta rebound.

The Journal of neuroscience : the official journal of the Society for Neuroscience • Vol. 30, Issue 19 • 2010
PMID: 20463236PMC: PMC2913973DOI: 10.1523/JNEUROSCI.1381-10.2010

Documentation