HomeProductsBioactive CompoundsNeuronal Signaling5-HT ReceptorIdalopirdine
Chemical structure of CAS 467459-31-0

Idalopirdine

CAS No.467459-31-0
MDL No.MFCD18633269
MFC20H19F5N2O
MW398.40
InChI KeyYBAWYTYNMZWMMJ-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.467459-31-0
Product NameIdalopirdine

Biological Targets

HTR6

Associated Conditions

Alzheimer disease·Cognitive impairment·schizophrenia
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Idalopirdine as a treatment for Alzheimer's disease.

Expert opinion on investigational drugs • Vol. 24, Issue 7 • 2015
PMID: 26022777DOI: 10.1517/13543784.2015.1052402

Safety and efficacy of idalopirdine, a 5-HT6 receptor antagonist, in patients with moderate Alzheimer's disease (LADDER): a randomised, double-blind, placebo-controlled phase 2 trial.

The Lancet. Neurology • Vol. 13, Issue 11 • 2014
PMID: 25297016DOI: 10.1016/S1474-4422(14)70198-X

Novel aza-analogous ergoline derived scaffolds as potent serotonin 5-HT₆ and dopamine D₂ receptor ligands.

Journal of medicinal chemistry • Vol. 57, Issue 13 • 2014
PMID: 24878269DOI: 10.1021/jm5003759

Serotonin 5-HT6 receptor antagonists for the treatment of cognitive deficiency in Alzheimer's disease.

Journal of medicinal chemistry • Vol. 57, Issue 17 • 2014
PMID: 24850589DOI: 10.1021/jm5003952

Documentation