Carbamate analogues of fumagillin as potent, targeted inhibitors of methionine aminopeptidase-2.
Journal of medicinal chemistry • Vol. 52, Issue 24 • 2009
An inhibitor of methionine aminopeptidase type-2, PPI-2458, ameliorates the pathophysiological disease processes of rheumatoid arthritis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] • Vol. 57, Issue 1 • 2008
Suppression of inflammation and structural damage in experimental arthritis through molecular targeted therapy with PPI-2458.
Arthritis and rheumatism • Vol. 56, Issue 3 • 2007
Inhibition of melanoma tumor growth by a pharmacological inhibitor of MetAP-2, PPI-2458.
International journal of oncology • Vol. 28, Issue 4 • 2006
