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Chemical structure of CAS 4033-27-6

Dihydrofolic Acid

In Stock•Starting at $97 for 5 mg•Purity ≥ 90%
CAS No.4033-27-6
MDL No.N/A
MFC19H21N7O6
MW443.40
InChI KeyOZRNSSUDZOLUSN-LBPRGKRZSA-N
CUSTOM SYNTHESIS

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
5 mg90%$97In Stock
10 mg90%$145In Stock
25 mg90%$285In Stock
50 mg90%$483In Stock
100 mg90%$817In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Dihydrofolic acid is a folic acid derivative that is converted to tetrahydrofolic acid by dihydrofolate reductase. It interacts with bacteria during cell division and is targeted by drugs to inhibit nucleic acid synthesis. It serves as an Escherichia coli and mouse metabolite. It is the conjugate acid of dihydrofolate(2-).

CAS No.4033-27-6
Product NameDihydrofolic Acid
IrritantIrritant
Signal Word:Warning
HCode:H315-H319-H335
PCode:P261-P264-P264+P265-P271-P280-P302+P352-P304+P340-P305+P351+P338-P319-P321-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Related Articles

Studies related to this compound and its mechanism of action

Folate requirements of the 2-keto-L-gulonic acid-producing strain Ketogulonigenium vulgare LMP P-20356 in L-sorbose/CSL medium.

Applied microbiology and biotechnology • Vol. 65, Issue 2 • 2004
PMID: 15293031DOI: 10.1007/s00253-004-1562-1

Sodium-dependent methotrexate carrier-1 is expressed in rat kidney: cloning and functional characterization.

American journal of physiology. Renal physiology • Vol. 286, Issue 3 • 2004
PMID: 14612385DOI: 10.1152/ajprenal.00257.2003

Microscale synthesis of isotopically labeled R-[6-xH]N5,N10-methylene-5,6,7,8-tetrahydrofolate as a cofactor for thymidylate synthase.

Analytical biochemistry • Vol. 328, Issue 1 • 2004
PMID: 15081906DOI: 10.1016/j.ab.2004.01.029

Inhibition of the rat breast cytosolic bioactivation of ethanol to acetaldehyde by some plant polyphenols and folic acid.

Nutrition and cancer • Vol. 49, Issue 1 • 2004
PMID: 15456641DOI: 10.1207/s15327914nc4901_13

Documentation

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