Efficacy of vestipitant, a neurokinin-1 receptor antagonist, in primary insomnia.
Sleep • Vol. 36, Issue 12 • 2013
Discovery and biological characterization of (2R,4S)-1'-acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4'-bipiperidine-1-carboxamide as a new potent and selective neurokinin 1 (NK1) receptor antagonist clinical candidate.
Journal of medicinal chemistry • Vol. 54, Issue 4 • 2011
The benzodiazepine diazepam demonstrates the usefulness of Syrian hamsters as a model for anxiety testing: evaluation of other classes of anxiolytics in comparison to diazepam.
Behavioural brain research • Vol. 218, Issue 1 • 2011
A randomized, controlled study comparing the effects of vestipitant or vestipitant and paroxetine combination in subjects with tinnitus.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology • Vol. 32, Issue 5 • 2011