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Gambogic AcidGambogic Acid

Gambogic Acid

CAS No.	2752-65-0
MDL No.	MFCD16878985
MF	C₃₈H₄₄O₈
MW	628.70
InChI Key	GEZHEQNLKAOMCA-RRZNCOCZSA-N

CUSTOM SYNTHESIS PRECLINICAL SUPPORT→

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Pack Size	Purity	Price	Availability	Action
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Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.	2752-65-0
Product Name	Gambogic Acid

Acute Toxic

Irritant

Signal Word:Danger

HCode:H301-H315-H319-H335

PCode:P261-P264-P264+P265-P270-P271-P280-P301+P316-P302+P352-P304+P340-P305+P351+P338-P319-P321-P330-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Studies related to this compound and its mechanism of action

Critical role of miR-26a-5p/Wnt5a signaling in gambogic acid-induced inhibition of gastric cancer.

Journal of biochemical and molecular toxicology • Vol. 35, Issue 4 • 2021

PMID: 33533530 DOI: 10.1002/jbt.22721

Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression.

Chemico-biological interactions • Vol. 235 • 2015

PMID: 25824409 DOI: 10.1016/j.cbi.2015.03.017

Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation.

Toxicology in vitro : an international journal published in association with BIBRA • Vol. 28, Issue 3 • 2014

PMID: 24373880 DOI: 10.1016/j.tiv.2013.12.008

The combination of proteasome inhibitors bortezomib and gambogic acid triggers synergistic cytotoxicity in vitro but not in vivo.

Toxicology letters • Vol. 224, Issue 3 • 2014

PMID: 24291039 DOI: 10.1016/j.toxlet.2013.11.021

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HomeHome
ProductsProducts
Bioactive CompoundsBioactive Compounds
ApoptosisApoptosis
Bcl-2Bcl-2
Gambogic AcidGambogic Acid

Gambogic Acid

CAS No.	2752-65-0
MDL No.	MFCD16878985
MF	C₃₈H₄₄O₈
MW	628.70
InChI Key	GEZHEQNLKAOMCA-RRZNCOCZSA-N

CUSTOM SYNTHESIS PRECLINICAL SUPPORT→

Pricing & Availability

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.	2752-65-0
Product Name	Gambogic Acid

Acute Toxic

Irritant

Signal Word:Danger

HCode:H301-H315-H319-H335

PCode:P261-P264-P264+P265-P270-P271-P280-P301+P316-P302+P352-P304+P340-P305+P351+P338-P319-P321-P330-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Studies related to this compound and its mechanism of action

Critical role of miR-26a-5p/Wnt5a signaling in gambogic acid-induced inhibition of gastric cancer.

Journal of biochemical and molecular toxicology • Vol. 35, Issue 4 • 2021

PMID: 33533530 DOI: 10.1002/jbt.22721

Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression.

Chemico-biological interactions • Vol. 235 • 2015

PMID: 25824409 DOI: 10.1016/j.cbi.2015.03.017

Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation.

Toxicology in vitro : an international journal published in association with BIBRA • Vol. 28, Issue 3 • 2014

PMID: 24373880 DOI: 10.1016/j.tiv.2013.12.008

The combination of proteasome inhibitors bortezomib and gambogic acid triggers synergistic cytotoxicity in vitro but not in vivo.

Toxicology letters • Vol. 224, Issue 3 • 2014

PMID: 24291039 DOI: 10.1016/j.toxlet.2013.11.021

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Gambogic Acid

Pricing & Availability

Product Information

Safety Information

Properties

Gambogic Acid

Pricing & Availability

Product Information

Safety Information

Properties

Documentation

Gambogic Acid

Pricing & Availability

Product Information

Safety Information

Properties

Related Articles

Critical role of miR-26a-5p/Wnt5a signaling in gambogic acid-induced inhibition of gastric cancer.

Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression.

Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation.

The combination of proteasome inhibitors bortezomib and gambogic acid triggers synergistic cytotoxicity in vitro but not in vivo.

Similar Products

Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-((2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino(4,3-b)indol-8-yl)-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12R,19alpha)-

Vinflunine Ditartrate

Navelbine ditartrate (TN)

Vinorelbine

Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity

Vinblastine Sulfate

Gambogic Acid

Pricing & Availability

Product Information

Safety Information

Properties

Related Articles

Critical role of miR-26a-5p/Wnt5a signaling in gambogic acid-induced inhibition of gastric cancer.

Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression.

Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation.

The combination of proteasome inhibitors bortezomib and gambogic acid triggers synergistic cytotoxicity in vitro but not in vivo.

Similar Products

Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-((2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino(4,3-b)indol-8-yl)-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12R,19alpha)-

Vinflunine Ditartrate

Navelbine ditartrate (TN)

Vinorelbine

Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity

Vinblastine Sulfate

Documentation