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Chemical structure of CAS 27314-97-2

Tirapazamine

In Stock•Starting at $12 for 1 mg•Purity ≥ 98%
CAS No.27314-97-2
MDL No.MFCD00132954
MFC7H6N4O2
MW178.15
InChI KeyORYDPOVDJJZGHQ-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg98%$12In Stock
10 mg98%$36In Stock
50 mg98%$69In Stock
100 mg98%$115In Stock
250 mg98%$284In Stock
1 g98%$815In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Tirapazamine is a 1,2,4-benzotriazine derivative with an amino group at position 3 and oxido substituents at positions 1 and 4. It functions as an antineoplastic agent, apoptosis inducer, and antibacterial agent. Tirapazamine is classified as a N-oxide, aromatic amine, and member of the benzotriazine class.

CAS No.27314-97-2
Product NameTirapazamine

Associated Conditions

lung cancer·upper aerodigestive tract neoplasm·small cell lung carcinoma·peritoneum cancer·cervical adenocarcinoma·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Analysis of DNA damage in individual cells.

Methods in cell biology • Vol. 64 • 2001
PMID: 11070842DOI: 10.1016/s0091-679x(01)64016-0

An investigation of the molecular basis for the synergistic interaction of tirapazamine and cisplatin.

International journal of radiation oncology, biology, physics • Vol. 49, Issue 1 • 2001
PMID: 11163512DOI: 10.1016/s0360-3016(00)01379-1

Therapeutic targets in radiotherapy.

International journal of radiation oncology, biology, physics • Vol. 49, Issue 2 • 2001
PMID: 11173124DOI: 10.1016/s0360-3016(00)01482-6

Mitochondrial dysfunction after aerobic exposure to the hypoxic cytotoxin tirapazamine.

Cancer research • Vol. 61, Issue 1 • 2001
PMID: 11196153

Documentation