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Chemical structure of CAS 2714434-21-4

YAP-TEAD-IN-3

In Stock•Starting at $150 for 5 mg•Purity ≥ 98%
CAS No.2714434-21-4
MDL No.N/A
MFC27H26ClF2N3O4
MW530.00
InChI KeyHUVOYQMXUNTUAI-DCFHFQCYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
5 mg98%$150In Stock
10 mg98%$252In Stock
25 mg98%$501In Stock
50 mg99%$887In Stock
100 mg99%$1506In Stock
250 mg99%$3008In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.2714434-21-4
Product NameYAP-TEAD-IN-3
Heavy Atom Count37Rotatable Bond Count7
Atom Stereo Count2Bond Stereo Count0
HBA6HBD3
TPSA92.710 ŲCharge0
Exact Mass529.15799Complexity1335.22
pKa7.130XLogP3.993

Related Articles

Studies related to this compound and its mechanism of action

Direct and selective pharmacological disruption of the YAP-TEAD interface by IAG933 inhibits Hippo-dependent and RAS-MAPK-altered cancers.

Nature cancer • Vol. 5, Issue 7 • 2024
PMID: 38565920PMC: PMC11286534DOI: 10.1038/s43018-024-00754-9

Leveraging Hot Spots of TEAD-Coregulator Interactions in the Design of Direct Small Molecule Protein-Protein Interaction Disruptors Targeting Hippo Pathway Signaling.

Pharmaceuticals (Basel, Switzerland) • Vol. 16, Issue 4 • 2023
PMID: 37111340PMC: PMC10146773DOI: 10.3390/ph16040583

Documentation

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