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Chemical structure of CAS 2457-80-9

5'-Methylthioadenosine

In Stock•Starting at $8 for 1 mg•Purity ≥ 95%
CAS No.2457-80-9
MDL No.MFCD00010533
MFC11H15N5O3S
MW297.34
InChI KeyWUUGFSXJNOTRMR-IOSLPCCCSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg97%$8In Stock
25 mg95%$27In Stock
50 mg95%$34In Stock
100 mg95%$40In Stock
250 mg95%$73In Stock
1 g95%$202In Stock
5 g95%$751In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

5'-S-methyl-5'-thioadenosine is adenosine with the hydroxy group at the C-5' position substituted by a methylthio (methylsulfanyl) group. It functions as a metabolite in humans, algae, Saccharomyces cerevisiae, Escherichia coli, and mice, and is functionally related to adenosine.

CAS No.2457-80-9
Product Name5'-Methylthioadenosine
IrritantIrritant
Signal Word:Warning
HCode:H302
PCode:P264-P270-P301+P317-P330-P501

Related Articles

Studies related to this compound and its mechanism of action

S-adenosylmethionine decarboxylase from Leishmania donovani. Molecular, genetic, and biochemical characterization of null mutants and overproducers.

The Journal of biological chemistry • Vol. 277, Issue 8 • 2002
PMID: 11734561DOI: 10.1074/jbc.M110118200

S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

Hepatology (Baltimore, Md.) • Vol. 35, Issue 2 • 2002
PMID: 11826399DOI: 10.1053/jhep.2002.30419

Methylthioadenosine phosphorylase gene deletions are common in osteosarcoma.

Clinical cancer research : an official journal of the American Association for Cancer Research • Vol. 8, Issue 3 • 2002
PMID: 11895909

Deletion of dinucleotide repeat (Delta 14 allele) in the methylthioadenosine phosphorylase (MTAP) promoter and the allelotype of MTAP promoter in the Japanese population.

Japanese journal of cancer research : Gann • Vol. 93, Issue 4 • 2002
PMID: 11985785PMC: PMC5927014DOI: 10.1111/j.1349-7006.2002.tb01266.x

Documentation

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