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Chemical structure of CAS 2416131-46-7

NX-2127

In Stock•Starting at $132 for 25 mg•Purity ≥ 98%
CAS No.2416131-46-7
MDL No.N/A
MFC39H45N9O5
MW719.80
InChI KeyXLWJWCMQMBVNSG-ACXKHFGCSA-N
CUSTOM SYNTHESIS

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
25 mg98%$132In Stock
50 mg98%$221In Stock
100 mg98%$375In Stock
250 mg98%$636In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.2416131-46-7
Product NameNX-2127
Heavy Atom Count53Rotatable Bond Count9
Atom Stereo Count2Bond Stereo Count0
HBA11HBD3
TPSA174.170 ŲCharge0
Exact Mass719.35437Complexity1937.54
pKa7.130XLogP3.417

Related Articles

Studies related to this compound and its mechanism of action

Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies.

Journal of medicinal chemistry • Vol. 67, Issue 4 • 2024
PMID: 38300987DOI: 10.1021/acs.jmedchem.3c01007

The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology.

Immunology • Vol. 160, Issue 1 • 2020
PMID: 32020584PMC: PMC7160657DOI: 10.1111/imm.13175

Effect of osmotic pressure, ionic strength and dibutyryl cyclic adenosine monophosphate on the adhesion of hen erythrocytes.

Blut • Vol. 33, Issue 1 • 1976
PMID: 10025DOI: 10.1007/BF01005212

Documentation

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