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Chemical structure of CAS 2245053-57-8

Etavopivat

In Stock•Starting at $157 for 25 mg•Purity ≥ 99%
CAS No.2245053-57-8
MDL No.MFCD34578328
MFC22H23N3O6S
MW457.50
InChI KeyKZFFYEPYCVDOGE-LJQANCHMSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
25 mg99%$157In Stock
50 mg99%$278In Stock
100 mg99%$470In Stock
250 mg99%$889In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.2245053-57-8
Product NameEtavopivat

Biological Targets

PKLR

Associated Conditions

Thalassemia·myelodysplastic syndrome·liver disease·sickle cell disease
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Etavopivat, a Pyruvate Kinase Activator in Red Blood Cells, for the Treatment of Sickle Cell Disease.

The Journal of pharmacology and experimental therapeutics • Vol. 380, Issue 3 • 2022
PMID: 35031585DOI: 10.1124/jpet.121.000743

Safety, Pharmacokinetics, and Pharmacodynamics of Etavopivat (FT-4202), an Allosteric Activator of Pyruvate Kinase-R, in Healthy Adults: A Randomized, Placebo-Controlled, Double-Blind, First-in-Human Phase 1 Trial.

Clinical pharmacology in drug development • Vol. 11, Issue 5 • 2022
PMID: 35019238PMC: PMC9306898DOI: 10.1002/cpdd.1058

Documentation