Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies.
Cancer cell • Vol. 41, Issue 12 • 2023
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines.
Bioorganic chemistry • Vol. 124 • 2022
Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer.
Journal of medicinal chemistry • Vol. 65, Issue 1 • 2022
Targeting the p300/CBP Axis in Lethal Prostate Cancer.
Cancer discovery • Vol. 11, Issue 5 • 2021