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Chemical structure of CAS 214764-26-8

KW-7158

CAS No.214764-26-8
MDL No.N/A
MFC16H12F3NO5S2
MW419.40
InChI KeyNAFSYPCVPLWHFY-HNNXBMFYSA-N
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Product Information

CAS No.214764-26-8
Product NameKW-7158
Heavy Atom Count27Rotatable Bond Count2
Atom Stereo Count1Bond Stereo Count0
HBA6HBD2
TPSA100.540 ŲCharge0
Exact Mass419.01090Complexity1054.25
pKa7.130XLogP2.518

Related Articles

Studies related to this compound and its mechanism of action

Kv4 Channels Underlie the Subthreshold-Operating A-type K-current in Nociceptive Dorsal Root Ganglion Neurons.

Frontiers in molecular neuroscience • Vol. 2 • 2009
PMID: 19668710PMC: PMC2724030DOI: 10.3389/neuro.02.003.2009

KW-7158 [(2S)-(+)-3,3,3-trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propanamide] enhances A-type K+ currents in neurons of the dorsal root ganglion of the adult rat.

The Journal of pharmacology and experimental therapeutics • Vol. 310, Issue 1 • 2004
PMID: 15010502DOI: 10.1124/jpet.104.065409

Effect of KW-7158, a putative afferent nerve inhibitor, on bladder and vesico-vascular reflexes in rats.

Brain research • Vol. 946, Issue 1 • 2002
PMID: 12133596DOI: 10.1016/s0006-8993(02)02828-7

Documentation

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