Darunavir is an N,N-disubstituted benzenesulfonamide with an unsubstituted amino group at the 4-position, used in the treatment of HIV infection. As a second-generation HIV protease inhibitor, it is designed to form strong interactions with the protease enzyme from various HIV strains, including those from treatment-experienced patients with multiple resistance mutations. It functions as a HIV protease inhibitor and antiviral drug, and is classified as a furofuran, carbamate ester, and sulfonamide.
