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Chemical structure of CAS 1983970-12-2

Uproleselan

CAS No.1983970-12-2
MDL No.N/A
MFC60H109N3O27
MW1304.50
InChI KeyLYSYOXNOOPBOSC-NGSKMYNLSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1983970-12-2
Product NameUproleselan

Biological Targets

SELE

Associated Conditions

deep vein thrombosis·acute myeloid leukemia·multiple myeloma·COVID-19
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Targeting E-selectin to Tackle Cancer Using Uproleselan.

Cancers • Vol. 13, Issue 2 • 2021
PMID: 33477563PMC: PMC7831123DOI: 10.3390/cancers13020335

Use of GMI-1271, an E-selectin antagonist, in healthy subjects and in 2 patients with calf vein thrombosis.

Research and practice in thrombosis and haemostasis • Vol. 4, Issue 2 • 2020
PMID: 32110749PMC: PMC7040550DOI: 10.1002/rth2.12279

A new way to treat proximal deep venous thrombosis using E-selectin inhibition.

Journal of vascular surgery. Venous and lymphatic disorders • Vol. 8, Issue 2 • 2020
PMID: 32067728PMC: PMC9006622DOI: 10.1016/j.jvsv.2019.08.016

E-selectin ligands recognised by HECA452 induce drug resistance in myeloma, which is overcome by the E-selectin antagonist, GMI-1271.

Leukemia • Vol. 31, Issue 12 • 2017
PMID: 28439107PMC: PMC5729350DOI: 10.1038/leu.2017.123

Documentation

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