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Chemical structure of CAS 1898206-17-1

Safusidenib

CAS No.1898206-17-1
MDL No.N/A
MFC25H18Cl3FN2O4
MW535.80
InChI KeyBOOMBLZEOHXPPX-BQYQJAHWSA-N
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Product Information

CAS No.1898206-17-1
Product NameSafusidenib

Biological Targets

IDH1

Associated Conditions

Paraganglioma·neoplasm
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model.

Molecular cancer therapeutics • Vol. 19, Issue 2 • 2020
PMID: 31727689DOI: 10.1158/1535-7163.MCT-18-1349

Selective inhibition of mutant IDH1 by DS-1001b ameliorates aberrant histone modifications and impairs tumor activity in chondrosarcoma.

Oncogene • Vol. 38, Issue 42 • 2019
PMID: 31406254DOI: 10.1038/s41388-019-0929-9

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