A potent, selective, and orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models.
The Journal of biological chemistry • Vol. 293, Issue 5 • 2018
Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR mouse model of atherosclerosis.
Clinical science (London, England : 1979) • Vol. 131, Issue 20 • 2017
The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues.
NPJ Regenerative medicine • Vol. 2 • 2017
Functional properties of Claramine: a novel PTP1B inhibitor and insulin-mimetic compound.
Biochemical and biophysical research communications • Vol. 458, Issue 1 • 2015
