Product Information

Satavaptan is a vasopressin V2 receptor antagonist used to improve hyponatremia in patients with cirrhosis, congestive heart failure, and syndrome of inappropriate antidiuresis. It functions as a vasopressin receptor antagonist and aquaretic. Chemically, it is a morpholine, aromatic ether, benzamide, secondary carboxamide, monomethoxybenzene, sulfonamide, and oxaspiro compound.

CAS No.	185913-78-4
Product Name	Satavaptan

Heavy Atom Count	45	Rotatable Bond Count	10
Atom Stereo Count	0	Bond Stereo Count	0
HBA	9	HBD	1
TPSA	123.710 Å²	Charge	0
Exact Mass	643.29274	Complexity	1506.28
pKa	5.875	XLogP	3.887

Satavaptan

CAS No.	185913-78-4
MDL No.	N/A
MF	C₃₃H₄₅N₃O₈S
MW	643.80
InChI Key	QKXJWFOKVQWEDZ-UHFFFAOYSA-N

CUSTOM SYNTHESIS

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Pack Size	Purity	Price	Availability	Action
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Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.	185913-78-4
Product Name	Satavaptan

Heavy Atom Count	45	Rotatable Bond Count	10
Atom Stereo Count	0	Bond Stereo Count	0
HBA	9	HBD	1
TPSA	123.710 Å²	Charge	0
Exact Mass	643.29274	Complexity	1506.28
pKa	5.875	XLogP	3.887

Satavaptan

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Satavaptan

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Documentation

Satavaptan

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Related Articles

Successful long-term treatment of hyponatremia in syndrome of inappropriate antidiuretic hormone secretion with satavaptan (SR121463B), an orally active nonpeptide vasopressin V2-receptor antagonist.

Effects of YM471, a nonpeptide AVP V(1A) and V(2) receptor antagonist, on human AVP receptor subtypes expressed in CHO cells and oxytocin receptors in human uterine smooth muscle cells.

Binding properties of a selective tritiated vasopressin V2 receptor antagonist, [H]-SR 121463.

Receptor binding of oxytocin and vasopressin antagonists and inhibitory effects on isolated myometrium from preterm and term pregnant women.

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Satavaptan

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Product Information

Properties

Related Articles

Successful long-term treatment of hyponatremia in syndrome of inappropriate antidiuretic hormone secretion with satavaptan (SR121463B), an orally active nonpeptide vasopressin V2-receptor antagonist.

Effects of YM471, a nonpeptide AVP V(1A) and V(2) receptor antagonist, on human AVP receptor subtypes expressed in CHO cells and oxytocin receptors in human uterine smooth muscle cells.

Binding properties of a selective tritiated vasopressin V2 receptor antagonist, [H]-SR 121463.

Receptor binding of oxytocin and vasopressin antagonists and inhibitory effects on isolated myometrium from preterm and term pregnant women.

Similar Products

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Documentation