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Chemical structure of CAS 183718-77-6

(5Z,8Z,11Z,14Z)-N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide

In Stock•Starting at $125 for 5 mg
CAS No.183718-77-6
MDL No.MFCD03095721
MFC26H37NO2
MW395.60
InChI KeyIJBZOOZRAXHERC-DOFZRALJSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
5 mgTo Be Confirmed$125In Stock
25 mgTo Be Confirmed$455In Stock
100 mgTo Be Confirmed$1402In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

AM404 is an anilide.

CAS No.183718-77-6
Product Name(5Z,8Z,11Z,14Z)-N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide
Heavy Atom Count29Rotatable Bond Count15
Atom Stereo Count0Bond Stereo Count4
HBA2HBD2
TPSA49.330 ŲCharge0
Exact Mass395.28243Complexity653.79
pKa8.189XLogP7.476

Related Articles

Studies related to this compound and its mechanism of action

An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact.

Journal of pain research • Vol. 16 • 2023
PMID: 37016715PMC: PMC10066900DOI: 10.2147/JPR.S393809

Modification of TRPV4 activity by acetaminophen.

Heliyon • Vol. 6, Issue 1 • 2020
PMID: 32051870PMC: PMC7002858DOI: 10.1016/j.heliyon.2020.e03301

"TRPV1 is a component of the atrial natriuretic signaling complex, and using orally delivered antagonists, presents a valid therapeutic target in the longitudinal reversal and treatment of cardiac hypertrophy and heart failure".

Channels (Austin, Tex.) • Vol. 13, Issue 1 • 2019
PMID: 30424709PMC: PMC6298697DOI: 10.1080/19336950.2018.1547611

Self-administration of the anandamide transport inhibitor AM404 by squirrel monkeys.

Psychopharmacology • Vol. 233, Issue 10 • 2016
PMID: 26803499PMC: PMC4846479DOI: 10.1007/s00213-016-4211-3

Documentation

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