HomeProductsBioactive CompoundsCell CycleDNA/RNA SynthesisH3B-8800
Chemical structure of CAS 1825302-42-8

H3B-8800

In Stock•Starting at $614 for 1 mg•Purity ≥ 98.31%
CAS No.1825302-42-8
MDL No.N/A
MFC31H45N3O6
MW555.70
InChI KeyYOIQWBAHJZGRFW-WVRLKXNASA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg98.31% ;$614In Stock
5 mg98.31% ;$1460In Stock
10 mg98.31% ;$1973In Stock
25 mg98.31% ;$2900In Stock
50 mg98.31% ;$3926In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1825302-42-8
Product NameH3B-8800
Heavy Atom Count40Rotatable Bond Count5
Atom Stereo Count6Bond Stereo Count3
HBA8HBD2
TPSA112.430 ŲCharge0
Exact Mass555.33084Complexity1062.09
pKa11.433XLogP3.840

Related Articles

Studies related to this compound and its mechanism of action

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers.

Nature medicine • Vol. 24, Issue 4 • 2018
PMID: 29457796PMC: PMC6730556DOI: 10.1038/nm.4493

Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.

PLoS genetics • Vol. 12, Issue 10 • 2016
PMID: 27776121PMC: PMC5077151DOI: 10.1371/journal.pgen.1006384

Frequent pathway mutations of splicing machinery in myelodysplasia.

Nature • Vol. 478, Issue 7367 • 2011
PMID: 21909114DOI: 10.1038/nature10496

Hepatic haematoma in polyarteritis nodosa.

The British journal of radiology • Vol. 49, Issue 578 • 1976
PMID: 7340DOI: 10.1259/0007-1285-49-578-184

Documentation