DempoChem Logo
  1. HomeHome
  2. /ProductsProducts
  3. /Building BlocksBuilding Blocks
  4. /Heterocyclic ScaffoldsHeterocyclic Scaffolds
  5. /PyrrolesPyrroles
  6. /S-18986S-18986
Chemical structure of CAS 175340-20-2

S-18986

In Stock•Starting at $375 for 10 mg•Purity ≥ 98%
CAS No.175340-20-2
MDL No.N/A
MFC10H12N2O2S
MW224.28
InChI KeyMNTIJYGEITVWHU-SNVBAGLBSA-N
CUSTOM SYNTHESIS

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
10 mg98%$375In Stock
25 mg98%$747In Stock
100 mg98%$2071In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.175340-20-2
Product NameS-18986
Heavy Atom Count15Rotatable Bond Count0
Atom Stereo Count1Bond Stereo Count0
HBA3HBD1
TPSA49.410 ŲCharge0
Exact Mass224.06195Complexity497.90
pKa5.875XLogP0.905

Related Articles

Studies related to this compound and its mechanism of action

DRUG FOCUS: S 18986: A positive allosteric modulator of AMPA-type glutamate receptors pharmacological profile of a novel cognitive enhancer.

CNS neuroscience & therapeutics • Vol. 16, Issue 5 • 2010
PMID: 21050420PMC: PMC6493918DOI: 10.1111/j.1755-5949.2009.00088.x

(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices.

European journal of pharmacology • Vol. 401, Issue 2 • 2000
PMID: 10924919DOI: 10.1016/s0014-2999(00)00433-7

Documentation

Your Partner for
Complex Chemistry
logo
  • About Us
  • Perspectives
  • Products
  • Contact
  • Preclinical Development
  • Technologies
  • Custom Synthesis
Ready to start your project?

Provide your target molecule or project specifications to align on a tailored development and scale-up pathway with our scientific team.

START A PROJECT
Westerstraat 10, 3016 DH, Rotterdam, The Netherlands
Westerstraat 10, 3016 DH, Rotterdam, The Netherlands
logo

All products are supplied strictly for research and development use only and are not intended for human or veterinary administration, diagnostic use, or therapeutic use. Preclinical and related services are provided solely for research and development purposes and do not constitute clinical diagnosis, treatment, or veterinary care.

©2026 DempoChem. All Rights Reserved.
DHLFedExUPSPostNL
CLIENT PORTAL|TERMS AND CONDITIONS|PRIVACY POLICY|
  • Products
    • CDMO Compounds
    • API & Candidates
  • Services
    CDMO & Manufacturing
    • Custom Synthesis
    • Process Development
    • Lab To Pilot
    • Commercialization
    • Generic APIs
    CRO
    • Preclinical
    • Pharmacology & Efficacy
    • DMPK & Bioanalysis
    • Toxicology & Safety
    • Disease Models
    Technologies
    • High-Potent
    • Chiral Synthesis
    • Cloud Synthesis
    • Fermentation
    • Flow Chemistry
    • Biocatalysis
    Support
    • Regulatory Support
    • Supply Chain Solutions
  • About
  • Perspectives
  • Contact