| CAS No. | 1698055-85-4 |
|---|---|
| MDL No. | N/A |
| MF | C21H17ClF2N4O2 |
| MW | 430.80 |
| InChI Key | ZRPZPNYZFSJUPA-UHFFFAOYSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
ARS-1620 is a qinazoline derivative with chloro and fluoro substituents at positions 6 and 8, respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. It is a potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor that targets the KRAS gene with high potency in cells and animals. It functions as an inhibitor, antiviral agent, and antineoplastic agent.
| CAS No. | 1698055-85-4 |
|---|---|
| Product Name | Ars-1620 |
| Heavy Atom Count | 30 | Rotatable Bond Count | 3 |
| Atom Stereo Count | 0 | Bond Stereo Count | 0 |
| HBA | 5 | HBD | 1 |
| TPSA | 69.560 Ų | Charge | 0 |
| Exact Mass | 430.10081 | Complexity | 1143.19 |
| pKa | 5.245 | XLogP | 3.769 |
