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Chemical structure of CAS 168266-90-8

Vofopitant

In Stock•Starting at $205 for 1 mg
CAS No.168266-90-8
MDL No.N/A
MFC21H23F3N6O
MW432.40
InChI KeyXILNRORTJVDYRH-HKUYNNGSSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mgTo Be Confirmed$205In Stock
2 mgTo Be Confirmed$293In Stock
5 mgTo Be Confirmed$475In Stock
10 mgTo Be Confirmed$700In Stock
25 mgTo Be Confirmed$1120In Stock
50 mgTo Be Confirmed$1507In Stock
100 mgTo Be Confirmed$2026In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.168266-90-8
Product NameVofopitant

Biological Targets

TACR1

Associated Conditions

Sleep Disorder·bipolar disorder·post-traumatic stress disorder
* The information provided here is compiled from public sources and is for reference only.

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Studies related to this compound and its mechanism of action

Discovery and biological characterization of (2R,4S)-1'-acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-4,4'-bipiperidine-1-carboxamide as a new potent and selective neurokinin 1 (NK1) receptor antagonist clinical candidate.

Journal of medicinal chemistry • Vol. 54, Issue 4 • 2011
PMID: 21229983DOI: 10.1021/jm1013264

Stress-induced increase of cortical dopamine metabolism: attenuation by a tachykinin NK1 receptor antagonist.

European journal of pharmacology • Vol. 484, Issue 1 • 2004
PMID: 14729382DOI: 10.1016/j.ejphar.2003.10.057

Role of tachykinin receptors in the central processing of afferent input from the acid-threatened rat stomach.

Regulatory peptides • Vol. 102, Issue 2-3 • 2001
PMID: 11730984DOI: 10.1016/s0167-0115(01)00309-3

Nitric oxide and NK(1)-tachykinin receptors in cyclophosphamide-induced cystitis, in rats.

The Journal of pharmacology and experimental therapeutics • Vol. 295, Issue 2 • 2000
PMID: 11046124

Documentation

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