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Chemical structure of CAS 1643913-93-2

Padnarsertib

CAS No.1643913-93-2
MDL No.MFCD30207881
MFC35H29F3N4O3
MW610.60
InChI KeyMRFOPLWJZULAQD-SWGQDTFXSA-N
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Product Information

CAS No.1643913-93-2
Product NamePadnarsertib

Associated Conditions

acute myeloid leukemia·non-Hodgkins lymphoma·neoplasm
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia.

Leukemia • Vol. 32, Issue 3 • 2018
PMID: 28904384DOI: 10.1038/leu.2017.281

A novel orally bioavailable compound KPT-9274 inhibits PAK4, and blocks triple negative breast cancer tumor growth.

Scientific reports • Vol. 7 • 2017
PMID: 28198380PMC: PMC5309789DOI: 10.1038/srep42555

Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma.

Molecular cancer therapeutics • Vol. 16, Issue 1 • 2017
PMID: 28062705PMC: PMC5221563DOI: 10.1158/1535-7163.MCT-16-0205

Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth.

Molecular cancer therapeutics • Vol. 15, Issue 9 • 2016
PMID: 27390344PMC: PMC5010932DOI: 10.1158/1535-7163.MCT-16-0197

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