| CAS No. | 1632250-49-7 |
|---|---|
| MDL No. | N/A |
| MF | C22H20ClN7O |
| MW | 433.90 |
| InChI Key | FDTXHWQFIXYHCL-QGZVFWFLSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| 1 mg | To Be Confirmed | $88 | In Stock | |
| 5 mg | To Be Confirmed | $212 | In Stock | |
| 10 mg | To Be Confirmed | $320 | In Stock | |
| 25 mg | To Be Confirmed | $527 | In Stock | |
| 50 mg | To Be Confirmed | $752 | In Stock | |
| 100 mg | To Be Confirmed | $1020 | In Stock | |
| Custom synthesis and bulk supply options are available upon request. | ||||
PF-06446846 is a triazolopyridine, specifically 3H-[1,2,3]triazolo[4,5-b]pyridine, substituted at position 3 with a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group. It is a potent PCSK9 inhibitor, acting as an antilipemic drug and EC 3.4.21.61 (kexin) inhibitor. It is a monochloropyridine, a piperidine, a tertiary carboxamide, a benzamide, and a triazolopyridine.
| CAS No. | 1632250-49-7 |
|---|---|
| Product Name | PF-06446846 |
| Heavy Atom Count | 31 | Rotatable Bond Count | 4 |
| Atom Stereo Count | 1 | Bond Stereo Count | 0 |
| HBA | 7 | HBD | 1 |
| TPSA | 88.830 Ų | Charge | 0 |
| Exact Mass | 433.14179 | Complexity | 1218.01 |
| pKa | 5.875 | XLogP | 3.263 |