Chemical structure of CAS 1628730-49-3

Praliciguat

In StockStarting at $311 for 1 mgPurity ≥ 98%
CAS No.1628730-49-3
MDL No.N/A
MFC21H14F8N6O2
MW534.40
InChI KeyCYSJNTQNMDWAJV-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg98%$311In Stock
5 mg98%$783In Stock
10 mg98%$1131In Stock
25 mg98%$1746In Stock
50 mg98%$2260In Stock
100 mg98%$3080In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Praliciguat is a 5-fluoro-2-(1H-pyrazol-3-yl)pyrimidine substituted with a 2-fluorobenzyl group at position 1, a 1,2-oxazol-3-yl group at position 5, and a [3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propyl]nitrilo group at position 4. It is a soluble guanylate cyclase stimulator under clinical development for heart failure with preserved ejection fraction. It functions as a soluble guanylate cyclase activator, anti-inflammatory agent, vasodilator, and antihypertensive. It belongs to isoxazoles, pyrazoles, organofluorine compounds, aminopyrimidines, tertiary alcohols, secondary amino compounds, and monofluorobenzenes.

CAS No.1628730-49-3
Product NamePraliciguat

Biological Targets

GUCY1B1·GUCY1B2·GUCY1A2·GUCY1A1

Associated Conditions

heart failure
* The information provided here is compiled from public sources and is for reference only.