Product Information

CAS No.	145969-30-8
Product Name	Opc-14523

Heavy Atom Count	29	Rotatable Bond Count	6
Atom Stereo Count	0	Bond Stereo Count	0
HBA	4	HBD	0
TPSA	36.020 Å²	Charge	0
Exact Mass	413.18700	Complexity	864.95
pKa	5.875	XLogP	3.840

Studies related to this compound and its mechanism of action

Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review.

Journal of pharmacy & bioallied sciences • Vol. 3, Issue 2 • 2011

PMID: 21687347 PMC: PMC3103913 DOI: 10.4103/0975-7406.80765

Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors.

Journal of psychopharmacology (Oxford, England) • Vol. 21, Issue 1 • 2007

PMID: 16533864 DOI: 10.1177/0269881106063996

In vitro profile of the antidepressant candidate OPC-14523 at rat and human 5-HT1A receptors.

European journal of pharmacology • Vol. 517, Issue 3 • 2005

PMID: 15985260 DOI: 10.1016/j.ejphar.2005.05.035

Effects of the potential antidepressant OPC-14523 [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate] a combined sigma and 5-HT1A ligand: modulation of neuronal activity in the dorsal raphe nucleus.

The Journal of pharmacology and experimental therapeutics • Vol. 310, Issue 2 • 2004

PMID: 15044555 DOI: 10.1124/jpet.104.066472

Opc-14523

CAS No.	145969-30-8
MDL No.	N/A
MF	C₂₃H₂₈ClN₃O₂
MW	413.90
InChI Key	TZZGTNZBLPCBIS-UHFFFAOYSA-N

CUSTOM SYNTHESIS PRECLINICAL SUPPORT

Pricing & Availability

Pack Size	Purity	Price	Availability	Action
-	-	On Request	On Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.	145969-30-8
Product Name	Opc-14523

Heavy Atom Count	29	Rotatable Bond Count	6
Atom Stereo Count	0	Bond Stereo Count	0
HBA	4	HBD	0
TPSA	36.020 Å²	Charge	0
Exact Mass	413.18700	Complexity	864.95
pKa	5.875	XLogP	3.840

Opc-14523

Pricing & Availability

Product Information

Properties

Opc-14523

Pricing & Availability

Product Information

Properties

Documentation

Opc-14523

Pricing & Availability

Product Information

Properties

Related Articles

Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review.

Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors.

In vitro profile of the antidepressant candidate OPC-14523 at rat and human 5-HT1A receptors.

Effects of the potential antidepressant OPC-14523 [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate] a combined sigma and 5-HT1A ligand: modulation of neuronal activity in the dorsal raphe nucleus.

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Opc-14523

Pricing & Availability

Product Information

Properties

Related Articles

Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review.

Effects of OPC-14523, a combined sigma and 5-HT1a ligand, on pre- and post-synaptic 5-HT1a receptors.

In vitro profile of the antidepressant candidate OPC-14523 at rat and human 5-HT1A receptors.

Effects of the potential antidepressant OPC-14523 [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate] a combined sigma and 5-HT1A ligand: modulation of neuronal activity in the dorsal raphe nucleus.

Similar Products

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Trazodone

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Documentation