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Chemical structure of CAS 1446321-46-5

Voxelotor

CAS No.1446321-46-5
MDL No.MFCD29053764
MFC19H19N3O3
MW337.40
InChI KeyFWCVZAQENIZVMY-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1446321-46-5
Product NameVoxelotor

Biological Targets

HBA1·HBA2·HBB

Associated Conditions

kidney disease·anemia (phenotype)·anemia·liver disease·idiopathic pulmonary fibrosis·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

First case of DRESS (drug reaction with eosinophilia and systemic symptoms) associated with voxelotor.

American journal of hematology • Vol. 96, Issue 11 • 2021
PMID: 34478170PMC: PMC9316384DOI: 10.1002/ajh.26342

Voxelotor for the treatment of sickle cell disease.

Expert review of hematology • Vol. 14, Issue 3 • 2021
PMID: 33602029DOI: 10.1080/17474086.2021.1893688

Voxelotor: A Hemoglobin S Polymerization Inhibitor for the Treatment of Sickle Cell Disease.

Journal of the advanced practitioner in oncology • Vol. 11, Issue 8 • 2020
PMID: 33489427PMC: PMC7810265DOI: 10.6004/jadpro.2020.11.8.7

Blocking HbS Polymerization in SCD.

Cell • Vol. 180, Issue 5 • 2020
PMID: 32142671DOI: 10.1016/j.cell.2020.01.019

Documentation