| CAS No. | 1414943-88-6 |
|---|---|
| MDL No. | N/A |
| MF | C18H18FN5O2S |
| MW | 387.40 |
| InChI Key | ACWKGTGIJRCOOM-UHFFFAOYSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| 1 mg | 98% | $61 | In Stock | |
| 5 mg | 98% | $81 | In Stock | |
| 10 mg | 98% | $107 | In Stock | |
| 25 mg | 98% | $178 | In Stock | |
| 50 mg | 98% | $354 | In Stock | |
| 100 mg | 98% | $511 | In Stock | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Atuveciclib Racemate is a potent and highly selective PTEFb/CDK9 inhibitor with an IC50 of 13 nM for CDK9/CycT and a 100-fold selectivity ratio over CDK2/CDK9. It also inhibits GSK3 kinases with IC50 values of 45 nM for GSK3a and 87 nM for GSK3b.
| CAS No. | 1414943-88-6 |
|---|---|
| Product Name | Atuveciclib Racemate |
| Heavy Atom Count | 27 | Rotatable Bond Count | 6 |
| Atom Stereo Count | 1 | Bond Stereo Count | 0 |
| HBA | 7 | HBD | 2 |
| TPSA | 100.850 Ų | Charge | 0 |
| Exact Mass | 387.11652 | Complexity | 1072.85 |
| pKa | 7.130 | XLogP | 3.606 |
