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Chemical structure of CAS 1387560-01-1

Umibecestat

In Stock•Starting at $316 for 5 mg•Purity ≥ 99%
CAS No.1387560-01-1
MDL No.N/A
MFC19H15ClF7N5O2
MW513.80
InChI KeyPSBBWFNMHDUTRH-DLBZAZTESA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
5 mg99%$316In Stock
10 mg99%$536In Stock
25 mg99%$832In Stock
50 mg99%$1118In Stock
100 mg99%$1525In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1387560-01-1
Product NameUmibecestat
Heavy Atom Count34Rotatable Bond Count3
Atom Stereo Count2Bond Stereo Count0
HBA6HBD2
TPSA102.490 ŲCharge0
Exact Mass513.08025Complexity1170.70
pKa7.130XLogP4.464

Related Articles

Studies related to this compound and its mechanism of action

Discovery of Umibecestat (CNP520): A Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor for the Prevention of Alzheimer's Disease.

Journal of medicinal chemistry • Vol. 64, Issue 20 • 2021
PMID: 34648711DOI: 10.1021/acs.jmedchem.1c01300

The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease.

EMBO molecular medicine • Vol. 10, Issue 11 • 2018
PMID: 30224383PMC: PMC6220303DOI: 10.15252/emmm.201809316

A promising, novel, and unique BACE1 inhibitor emerges in the quest to prevent Alzheimer's disease.

EMBO molecular medicine • Vol. 10, Issue 11 • 2018
PMID: 30322841PMC: PMC6220261DOI: 10.15252/emmm.201809717

Documentation