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Chemical structure of CAS 1382979-44-3

Paxalisib

CAS No.1382979-44-3
MDL No.MFCD30187522
MFC18H22N8O2
MW382.40
InChI KeyLGWACEZVCMBSKW-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
- -On RequestOn Request
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1382979-44-3
Product NamePaxalisib

Biological Targets

PIK3R1·PIK3CB·PIK3CG·PIK3CA·PIK3R2·

Associated Conditions

glioblastoma multiforme·Central Nervous System Neoplasm·neoplasm·breast cancer
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR.

ACS medicinal chemistry letters • Vol. 7, Issue 4 • 2016
PMID: 27096040PMC: PMC4834666DOI: 10.1021/acsmedchemlett.6b00005

Oxidative biotransformation of 2-acetylaminofluorene in fetal and placental tissues of humans and monkeys. Correlations with aryl hydrocarbon hydroxylase activities.

Drug metabolism and disposition: the biological fate of chemicals • Vol. 3, Issue 6 • 1975
PMID: 1224

Documentation