New selective ligands of human cloned melatonin MT1 and MT2 receptors.
Naunyn-Schmiedeberg's archives of pharmacology • Vol. 367, Issue 6 • 2003
The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways.
The Journal of pharmacology and experimental therapeutics • Vol. 306, Issue 3 • 2003
Effect of agomelatine in the chronic mild stress model of depression in the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology • Vol. 28, Issue 4 • 2003
Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands.
Journal of medicinal chemistry • Vol. 46, Issue 7 • 2003