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Chemical structure of CAS 133865-88-0

Priralfinamide

In Stock•Starting at $94 for 5 mg•Purity ≥ 98%
CAS No.133865-88-0
MDL No.MFCD08272558
MFC17H19FN2O2
MW302.34
InChI KeyBHJIBOFHEFDSAU-LBPRGKRZSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
5 mg98%$94In Stock
50 mg98%$96In Stock
100 mg98%$160In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.133865-88-0
Product NamePriralfinamide

Biological Targets

GRIN1·GRIN2A·GRIN2B·GRIN2D·GRIN3B·

Associated Conditions

neuropathic pain·Pain
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Recent developments regarding voltage-gated sodium channel blockers for the treatment of inherited and acquired neuropathic pain syndromes.

Frontiers in pharmacology • Vol. 2 • 2011
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Disposition and metabolism of ralfinamide, a novel Na-channel blocker, in healthy male volunteers.

Pharmacology • Vol. 86, Issue 5-6 • 2010
PMID: 21071997DOI: 10.1159/000321322

Functional and pharmacological properties of human and rat NaV1.8 channels.

Neuropharmacology • Vol. 56, Issue 5 • 2009
PMID: 19371587DOI: 10.1016/j.neuropharm.2009.01.018

Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat.

Pain • Vol. 139, Issue 2 • 2008
PMID: 18583049DOI: 10.1016/j.pain.2008.04.020

Documentation

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