Zavegepant is a urea derivative in which both amino groups are replaced by 4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidin-1-yl and {(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl}amino groups. It is a calcitonin gene-related peptide receptor antagonist, with its hydrochloride salt approved by the FDA for the acute treatment of migraine. It is classified as a quinolone, piperidinecarboxamide, urea, N-acylpiperazine, piperidine, and indazole. It is also the conjugate base of zavegepant(1+).
