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Chemical structure of CAS 131175-87-6

Npc80142

In Stock•Starting at $18 for 1 g•Purity ≥ 95%
CAS No.131175-87-6
MDL No.N/A
MFC15H24O5
MW284.35
InChI KeyBJDCWCLMFKKGEE-HVDUHBCDSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 g95% (mix)$18In Stock
5 g95% (mix)$46In Stock
10 g95% (mix)$75In Stock
25 g95% (mix)$149In Stock
100 g95% (mix)$512In Stock
500 g95% (mix)$2037In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Dihydroartemisinin is a sesquiterpenoid compound used as an antimalarial drug.

CAS No.131175-87-6
Product NameNpc80142
Heavy Atom Count20Rotatable Bond Count0
Atom Stereo Count8Bond Stereo Count0
HBA5HBD1
TPSA57.150 ŲCharge0
Exact Mass284.16237Complexity411.07
pKa11.175XLogP2.187

Related Articles

Studies related to this compound and its mechanism of action

Application of higher throughput screening (HTS) inhibition assays to evaluate the interaction of antiparasitic drugs with cytochrome P450s.

Drug metabolism and disposition: the biological fate of chemicals • Vol. 29, Issue 1 • 2001
PMID: 11124226

Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin.

Journal of medicinal chemistry • Vol. 44, Issue 1 • 2001
PMID: 11141088DOI: 10.1021/jm000987f

The role of glutathione in the neurotoxicity of artemisinin derivatives in vitro.

Biochemical pharmacology • Vol. 61, Issue 4 • 2001
PMID: 11226374DOI: 10.1016/s0006-2952(00)00556-6

Possible modes of action of the artemisinin-type compounds.

Trends in parasitology • Vol. 17, Issue 3 • 2001
PMID: 11286794DOI: 10.1016/s1471-4922(00)01838-9

Documentation

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