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Chemical structure of CAS 128607-22-7

Ospemifene

CAS No.128607-22-7
MDL No.MFCD00871890
MFC24H23ClO2
MW378.90
InChI KeyLUMKNAVTFCDUIE-VHXPQNKSSA-N

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Product Information

Ospemifene is an organochlorine, aromatic ether, and primary alcohol compound that acts as a selective estrogen receptor modulator. It is used for the treatment of dyspareunia and functions as an estrogen receptor modulator, antineoplastic agent, and anti-inflammatory agent. It derives from a stilbene hydride.

CAS No.128607-22-7
Product NameOspemifene

Biological Targets

ESR2·ESR1

Associated Conditions

Atrophic Vaginitis·reproductive system disease·Dyspareunia·postmenopausal atrophic vaginitis·menopause·
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-gamma-inducible protein-10 by astrocytes exposed to inflammatory challenge in vitro.

Glia • Vol. 58, Issue 1 • 2010
PMID: 19533603DOI: 10.1002/glia.20904

Pharmacologic evaluation of ospemifene.

Expert opinion on drug metabolism & toxicology • Vol. 6, Issue 6 • 2010
PMID: 20429673DOI: 10.1517/17425255.2010.487483

Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro.

British journal of pharmacology • Vol. 151, Issue 3 • 2007
PMID: 17420779PMC: PMC2013975DOI: 10.1038/sj.bjp.0707232

Effects of ospemifene and raloxifene on biochemical markers of bone turnover in postmenopausal women.

Journal of bone and mineral metabolism • Vol. 24, Issue 4 • 2006
PMID: 16816926DOI: 10.1007/s00774-006-0689-9

Documentation

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