Idasanutlin
| CAS No. | 1229705-06-9 |
|---|---|
| MDL No. | MFCD26142931 |
| MF | C31H29Cl2F2N3O4 |
| MW | 616.50 |
| InChI Key | TVTXCJFHQKSQQM-LJQIRTBHSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
Idasanutlin is an orally available, small-molecule antagonist of MDM2 (mouse double minute 2), with potential antineoplastic activity. It binds to MDM2, preventing its interaction with the transcriptional activation domain of the tumor suppressor protein p53. This blocks MDM2-mediated enzymatic degradation of p53, restoring its transcriptional activity and potentially inducing tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is frequently overexpressed in cancer cells and is involved in their proliferation and survival.
| CAS No. | 1229705-06-9 |
|---|---|
| Product Name | Idasanutlin |
Biological Targets
TP53·MDM2
Associated Conditions
non-Hodgkins lymphoma·diffuse large B-cell lymphoma·breast cancer·follicular lymphoma·neoplasm·
* The information provided here is compiled from public sources and is for reference only.
