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Chemical structure of CAS 1229453-99-9

Acrizanib

In Stock•Starting at $75 for 1 mg•Purity ≥ 99%
CAS No.1229453-99-9
MDL No.N/A
MFC20H18F3N7O2
MW445.40
InChI KeyXPIHPLVWOUDMPF-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg99%$75In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1229453-99-9
Product NameAcrizanib
Heavy Atom Count32Rotatable Bond Count5
Atom Stereo Count0Bond Stereo Count0
HBA8HBD2
TPSA98.890 ŲCharge0
Exact Mass445.14741Complexity1279.92
pKa9.247XLogP3.776

Related Articles

Studies related to this compound and its mechanism of action

The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration.

Journal of medicinal chemistry • Vol. 61, Issue 4 • 2018
PMID: 29400470DOI: 10.1021/acs.jmedchem.7b01731

Documentation