Etrasimod
| CAS No. | 1206123-37-6 |
|---|---|
| MDL No. | MFCD28502134 |
| MF | C26H26F3NO3 |
| MW | 457.50 |
| InChI Key | MVGWUTBTXDYMND-QGZVFWFLSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
Etrasimod is an organic heterotricyclic compound with a 1,2,3,4-tetrahydrocyclopenta[b]indole core substituted by carboxymethyl and [4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy groups at positions 3R and 7, respectively. It is a potent and functional antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50 = 1.88 nM in CHO cells). It functions as an antibacterial agent, immunosuppressive agent, anti-inflammatory drug, and S1P1 receptor antagonist. It belongs to (trifluoromethyl)benzenes, cyclopentanes, aromatic ethers, monocarboxylic acids, and organic heterotricyclic compounds. It is the conjugate acid of etrasimod(1-).
| CAS No. | 1206123-37-6 |
|---|---|
| Product Name | Etrasimod |
Biological Targets
S1PR1·S1PR4·S1PR5
Associated Conditions
eosinophilic esophagitis·inflammatory bowel disease·atopic eczema·Crohn's disease·primary biliary cirrhosis·
* The information provided here is compiled from public sources and is for reference only.
