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Chemical structure of CAS 1193383-09-3

1-[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]pyrazole-4-carboxylic acid

In Stock•Starting at $29 for 1 mg•Purity ≥ 98%
CAS No.1193383-09-3
MDL No.MFCD25541711
MFC12H6ClF3N4O3
MW346.65
InChI KeyFXHHASJVTYRJHH-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg98+%$29In Stock
5 mg98+%$34In Stock
50 mg98+%$214In Stock
100 mg98+%$363In Stock
250 mg98+%$615In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1193383-09-3
Product Name1-[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]pyrazole-4-carboxylic acid
Heavy Atom Count23Rotatable Bond Count3
Atom Stereo Count0Bond Stereo Count0
HBA5HBD2
TPSA93.030 ŲCharge0
Exact Mass346.00805Complexity902.72
pKa0.577XLogP2.999

Related Articles

Studies related to this compound and its mechanism of action

The stabilization of hypoxia inducible factor modulates differentiation status and inhibits the proliferation of mouse embryonic stem cells.

Chemico-biological interactions • Vol. 244 • 2016
PMID: 26723917DOI: 10.1016/j.cbi.2015.12.007

Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor.

Molecular pharmacology • Vol. 79, Issue 6 • 2011
PMID: 21372172DOI: 10.1124/mol.110.070508

Documentation