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Chemical structure of CAS 114-86-3

Phenformin

In Stock•Starting at $34 for 100 mg•Purity ≥ 95%
CAS No.114-86-3
MDL No.MFCD00242966
MFC10H15N5
MW205.26
InChI KeyICFJFFQQTFMIBG-UHFFFAOYSA-N
CUSTOM SYNTHESISPRECLINICAL SUPPORT

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
100 mg≥95%$34In Stock
250 mg≥95%$50In Stock
1 g≥95%$120In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

Phenformin is a biguanide with a 2-phenylethyl group substituting one terminal nitrogen atom. It was an anti-diabetic drug withdrawn due to lactic acidosis risk. It functions as an antineoplastic agent, geroprotector, and hypoglycemic agent, and is related to other biguanides.

CAS No.114-86-3
Product NamePhenformin

Associated Conditions

melanoma·diabetes mellitus
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Phenformin suppresses calcium responses to glutamate and protects hippocampal neurons against excitotoxicity.

Experimental neurology • Vol. 175, Issue 1 • 2002
PMID: 12009768DOI: 10.1006/exnr.2002.7864

Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus.

The Cochrane database of systematic reviews, Issue 2 • 2002
PMID: 12076461DOI: 10.1002/14651858.CD002967

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin.

The Journal of pharmacology and experimental therapeutics • Vol. 302, Issue 2 • 2002
PMID: 12130709DOI: 10.1124/jpet.102.034140

Lactic acidosis update for critical care clinicians.

Journal of the American Society of Nephrology : JASN • Vol. 12 Suppl 17 • 2001
PMID: 11251027

Documentation

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