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Chemical structure of CAS 1127498-03-6

Jnj-40411813

In Stock•Starting at $25 for 1 mg•Purity ≥ 98%
CAS No.1127498-03-6
MDL No.MFCD22572363
MFC20H25ClN2O
MW344.90
InChI KeyHYOGJHCDLQSAHX-UHFFFAOYSA-N

Pricing & Availability

Pack SizePurityPriceAvailabilityAction
1 mg98+%$25In Stock
5 mg98%$55In Stock
10 mg98%$65In Stock
25 mg98%$106In Stock
50 mg98%$139In Stock
100 mg98%$235In Stock
250 mg98%$396In Stock
Custom synthesis and bulk supply options are available upon request.

Product Information

CAS No.1127498-03-6
Product NameJnj-40411813

Biological Targets

GRM2

Associated Conditions

Seizure·major depressive disorder·schizophrenia·perceptual disorders
* The information provided here is compiled from public sources and is for reference only.

Related Articles

Studies related to this compound and its mechanism of action

Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies.

Journal of psychopharmacology (Oxford, England) • Vol. 29, Issue 4 • 2015
PMID: 25735992DOI: 10.1177/0269881115573403

Preclinical evaluation of the antipsychotic potential of the mGlu2-positive allosteric modulator JNJ-40411813.

Pharmacology research & perspectives • Vol. 3, Issue 2 • 2015
PMID: 25692027PMC: PMC4324682DOI: 10.1002/prp2.97

Pharmacological and pharmacokinetic properties of JNJ-40411813, a positive allosteric modulator of the mGlu2 receptor.

Pharmacology research & perspectives • Vol. 3, Issue 1 • 2015
PMID: 25692015PMC: PMC4317228DOI: 10.1002/prp2.96

Discovery of 1-butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone (JNJ-40411813): a novel positive allosteric modulator of the metabotropic glutamate 2 receptor.

Journal of medicinal chemistry • Vol. 57, Issue 15 • 2014
PMID: 25032784DOI: 10.1021/jm500496m

Documentation