Tovorafenib
| CAS No. | 1096708-71-2 |
|---|---|
| MDL No. | MFCD22571730 |
| MF | C17H12Cl2F3N7O2S |
| MW | 506.30 |
| InChI Key | VWMJHAFYPMOMGF-ZCFIWIBFSA-N |
Pricing & Availability
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Product Information
TAK-580 is a 1,3-thiazolecarboxamide, specifically 2-[(1R)-1-aminoethyl]-1,3-thiazole-5-carboxylic acid, formed by the formal condensation of the carboxy group with the amino group of 5-chloro-4-(trifluoromethyl)pyridin-2-amine and the amino group with the carboxy group of 6-amino-5-chloropyrimidine-4-carboxylic acid. It is a pan-RAF kinase inhibitor in clinical development for radiographically recurrent or progressive low-grade glioma in children and young adults. It functions as an antineoplastic agent, apoptosis inducer, and B-Raf inhibitor. It is classified as a chloropyridine, organofluorine compound, secondary carboxamide, aminopyrimidine, pyrimidinecarboxamide, and 1,3-thiazolecarboxamide.
| CAS No. | 1096708-71-2 |
|---|---|
| Product Name | Tovorafenib |
Biological Targets
RAF1·BRAF·ARAF
Associated Conditions
adenocarcinoma·papillary thyroid carcinoma·non-small cell lung carcinoma·low grade glioma·urinary bladder cancer·
* The information provided here is compiled from public sources and is for reference only.
