| CAS No. | 1095173-27-5 |
|---|---|
| MDL No. | MFCD25976839 |
| MF | C21H22N6O |
| MW | 374.40 |
| InChI Key | SFNSLLSYNZWZQG-VQIMIIECSA-N |
| Pack Size | Purity | Price | Availability | Action |
|---|---|---|---|---|
| - | - | On Request | On Request | |
| Custom synthesis and bulk supply options are available upon request. | ||||
Glasdegib is a benzimidazole containing a (2R,4S)-4-{[(4-cyanophenyl)carbamoyl]amino}-1-methylpiperidin-2-yl group at position 2. It is a SMO receptor antagonist and Hedgehog signaling pathway inhibitor with an IC50 of 5 nM. Used in combination with low-dose cytarabine, it treats newly-diagnosed AML in adults aged >=75 years or with contraindications to standard chemotherapy. It is classified as a benzimidazole, piperidine, phenylurea, and nitrile, and functions as an antineoplastic agent.
| CAS No. | 1095173-27-5 |
|---|---|
| Product Name | Glasdegib |
